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Treatment for Young Adults With Anorexia Nervosa

Family-Based Treatment for Weight Restoration in Young Adults With Anorexia Nervosa

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01190423
Enrollment
22
Registered
2010-08-27
Start date
2010-07-31
Completion date
2016-04-30
Last updated
2018-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anorexia Nervosa

Keywords

AN

Brief summary

Temple University is conducting a National Institute of Health funded research study designed to develop and refine a family-based treatment manual for young adults with Anorexia Nervosa as well as assess the feasibility of this out-patient psychotherapy.

Detailed description

Anorexia Nervosa (AN) is a serious psychiatric illness that occurs in an estimated 0.5 to 3.7% of women. The illness severely affects physical, emotional, and social functioning. The mortality rates associated with this severely disabling condition are higher than those for any other psychiatric disorder and substantially higher than those expected in the general population. Lower weight at presentation, longer illness duration, and alcohol abuse are associated with a higher risk of mortality. Treatment-outcome for adult AN is poor with a quarter of adults with AN having poor outcome. In AN, promising outcomes are seen in family-based treatment (FBT) for adolescent patients who present between the ages of 12 to 18 with a short duration of illness. A manualized version of FBT has now been tested in several studies and case series, showing that well over 80% of participants had good or intermediate outcome at post-treatment. Despite its efficacy with adolescents, FBT has not been utilized with young adults. The purpose of this study is to develop and refine FBT to promote weight gain in young adults with Anorexia Nervosa.

Interventions

BEHAVIORALFamily Based Therapy for young adults

Individual and Group Therapy Sessions

Sponsors

National Institute of Mental Health (NIMH)
CollaboratorNIH
Temple University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
No

Inclusion criteria

* Meet DSM-IV criteria for AN (restricting/binge-purge type) (BMI 16.0-18.5) * Medically stable for outpatient treatment * Availability of at least one supportive adult of choice in study client's environment * Stable dose of psychotropic medication (8 weeks) for co-morbid condition

Exclusion criteria

* Associated physical illness that necessitates hospitalization * Psychotic illness or other mental illness requiring hospitalization * Current dependence on drugs or alcohol * Physical conditions (e.g. diabetes mellitus, pregnancy) known to influence eating or weight * Previous Family-Based Treatment for Anorexia

Design outcomes

Primary

MeasureTime frame
Weight (BMI)6 months of treatment

Secondary

MeasureTime frame
Changes in shape and weight concerns as measured with Eating Disorder Examination subscales18 therapy sessions or 6 months of treatment

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026