Lipid-lowering Therapy for Secondary Prevention in Patients Undergoing Elective Percutaneous Coronary Intervention (PCI)

LIPID-LOWERING THERAPY FOR SECONDARY PREVENTION IN PATIENTS UNDERGOING ELECTIVE PERCUTANEOUS CORONARY INTERVENTION (PCI) A 10-week, Open-label, Non-interventional Study of Total Cholesterol/LDL-cholesterol Management in Real Life in Coronary Patients Hospitalised for Elective PCI

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01190072

Enrollment

120

Registered

2010-08-27

Start date

2010-09-30

Completion date

2011-03-31

Last updated

2013-01-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

Blood lipids, percutaneous coronary intervention, lipid lowering treatment

Brief summary

The purpose of the study is to follow the management of blood lipids in patients with planned percutaneous coronary intervention (widening of coronary vessels) in a period from 6 to 10 weeks after the intervention.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Male or nonpregnant female * Coronary patient hospitalised for elective PCI * Hypercholesterolaemia defined as LDL-C ≥ 2 mmol/L

Exclusion criteria

* Any chronic inflammatory condition * Chronic anti-inflammatory pharmacotherapy (except low-dose ASA)

Design outcomes

Primary

Measure	Time frame
Serum total cholesterol concentration	Week 0
Serum LDL cholesterol concentration	Week 0

Secondary

Measure	Time frame
Proportion of patients achieving LDL-C < 2 mmol/L	Once during the time period between Week 6 and Week 10
Proportion of patients achieving total cholesterol < 4 mmol/L	Once during the time period between Week 6 and Week 10
Change of hsCRP levels from baseline	Once during the time period between Week 6 and Week 10

Countries

Slovenia

Outcome results