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Efficacy of Methylsulfonylmethane Supplementation on Osteoarthritis of The Knee: A Randomized Controlled Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01188213
Enrollment
Unknown
Registered
2010-08-25
Start date
Unknown
Completion date
Unknown
Last updated
2010-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Brief summary

The aim of this study was to determine the efficacy of methylsulfonylmethane (MSM) in treating patients with knee OA.

Interventions

DIETARY_SUPPLEMENTMethylsulfonylmethane (MSM)

Sponsors

Assaf-Harofeh Medical Center
Lead SponsorOTHER_GOV

Eligibility

Sex/Gender
ALL
Age
40 Years to 70 Years

Inclusion criteria

* symptomatic knee OA for at least 6 months according to the clinical criteria of the American College of Rheumatology (ACR) * radiographic confirmed knee OA according to the Kellgren & Lawrence scale

Exclusion criteria

* acute septic arthritis * inflammatory arthritis * any other type of arthritis * history of knee buckling or recent knee injury * lack of physical or mental bility to perform or comply with the treatment procedure * diabetes mellitus * fibromyalgia or other chronic pain syndromes * concurrent anti-coagulant/anti-platelet drugs * arthroscopy or intra-articular injections in the previous 3 months

Design outcomes

Primary

MeasureTime frame
WOMAC questionnaire—

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 28, 2026