Efficacy of Sprayable PEG Barrier in Gynecologic Laparoscopy

Polyethylene Glycol Adhesion Barrier Reduces Adhesions After Gynecologic Laparoscopy; a Prospective Randomized Controlled Pilot Study

Status

Terminated

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01187680

Enrollment

Registered

2010-08-24

Start date

2002-10-31

Completion date

2009-07-31

Last updated

2010-12-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peritoneal Adhesion, Nos, Postoperative Adhesion

Keywords

Tissue adhesions, Laparoscopy

Brief summary

The purpose of the study is to investigate whether sprayable PEG barrier is effective in reducing adhesions in laparoscopic gynecologic surgery.

Interventions

DEVICESpraygel

DEVICEControl

Good surgical technique, no adhesion barrier

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 40 Years

Healthy volunteers

Inclusion criteria

* \>18 years * Undergoing gynecologic laparoscopy

Exclusion criteria

* Suspected malignancy * Incomplete adhesiolysis during initial laparoscopy * Pregnancy * Lactating * Stage IV endometriosis

Design outcomes

Primary

Measure	Time frame	Description
successful adhesion prevention	—	Adhesion prevention was defined as successful if no de novo fromed adhesion were found at second look laparoscopy.

Secondary

Measure	Time frame	Description
Adhesion sites	—	Reduction in the number of sites covered with adhesions
LABS adhesion score	—	—

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026