Lung Perfusion With Oxygenated Blood During Aortic Clamping

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01186510

Acronym

PulPer-001-Sch

Enrollment

Registered

2010-08-23

Start date

2010-08-31

Completion date

2012-11-30

Last updated

2013-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pulmonary Dysfunction

Brief summary

Pulmonary dysfunction presumably linked to an inflammatory response is frequent after cardiac operations using cardiopulmonary bypass (CPB) and pulmonary hypoperfusion. Aim of the study: To evaluate the protective effect of continuous pulmonary perfusion with oxygenated blood during aortic crossclamping on the inflammatory response.

Interventions

PROCEDURElung perfusion

see literature of proceeding

PROCEDUREno lung perfusion

see literature of proceeding

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Age 18-80 ys * Cardiopulmonary bypass procedure * FEV1 \<80% * COPD \>II

Exclusion criteria

* Emergency cases

Design outcomes

Primary

Measure	Time frame
Inflammatory marker	5 days

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026