Tweens to Teens Project at Penn State

Gender Development in Early Adolescence: Prenatal Hormones and Family Socialization

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01184651

Acronym

T2T@PSU

Enrollment

188

Registered

2010-08-19

Start date

2009-08-31

Completion date

2013-07-31

Last updated

2018-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congenital Adrenal Hyperplasia

Keywords

Congenital Adrenal Hyperplasia, CAH, sex differences, adolescence, androgen, behavior, gender development

Brief summary

The goal of this study is to help investigators to understand more about the development of characteristics related to being male or female (what is called gender development). The investigators will study girls with congenital adrenal hyperplasia (CAH) aged 10 to 13 to learn more about the girls' interests and activities, thoughts and feeling about being female, and family relationships. This will help investigators to understand the ways in which gender development is shaped by hormones and family relationships.

Detailed description

Interviewers will visit girls in their home when it is convenient for the family. Girls will answer questions about the things they do and are interested in, how they think and feel, and complete some cognitive tasks. Girls will also provide saliva so we can examine their hormones and determine the CAH gene mutation they have. Parents will also be asked to complete questionnaires about their own activities and interests and about their daughter's behavior. Shortly after the home visit, interviewers will telephone girls and their parents on several days and ask what the girls did during the day.

Interventions

BEHAVIORALQuestionnaires/Interviews

Girls answer questions about activities and interests, school, feelings about being a girl, stage of physical development, and family relationships during a home interview , provide saliva samples, and participate in phone interviews to answer questions about daily activities .

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Age

10 Years to 13 Years

Healthy volunteers

Yes

Inclusion criteria

* Girls with classical or non-classical CAH due to 21-OHD * Girls will be aged 10-13 years at initial recruitment * Parents will include biological mothers and fathers as well as step-parents and/or other guardians/significant caregivers * Parents/guardians may range in age from 18 years of age to 65 years of age.

Exclusion criteria

* Girls who are not within the age range of 10-13 years old at initial recruitment * CAH not due to the 21-OHD form

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026