Acute Lung Injury After Aortic Valve Surgery

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01184313

Enrollment

100

Registered

2010-08-18

Start date

2010-09-30

Completion date

Unknown

Last updated

2010-09-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Injury

Keywords

aortic valve surgery, CPB, lung injury

Brief summary

The purpose of this prospective, randomized clinical trial is to understand and measure lung injuries caused by CPB in aortic valve surgery. Study questions: * Is there any correlation between the release of pro-inflammatory biomarkers and lung injury degree? * Is there any correlation between oxyhaemodynamic parameters and lung injury degree? * Is there any correlation between oxyhaemodynamic parameters and the release of pro-inflammatory biomarkers? * Are budesonide, erdostein and acetylcystein effective in the prevention of lung injuries?

Interventions

PROCEDUREaortic valve surgery with CPB

elective aortic valve surgery with CPB

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* elective aortic valve surgery patient * written consent

Exclusion criteria

* none

Design outcomes

Primary

Measure	Time frame
lung injury	within the first 3 days after surgery

Countries

Finland

Contacts

Primary ContactFausto Biancari, MD, PhD

fausto.biancari@ppshp.fi

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026