Attention Deficit Disorders, Autism Spectrum Disorders, Mood Disorders, Sleep Disorders
Conditions
Keywords
Circadian Disorders, Autism Spectrum Disorders, Mood Disorders, Executive Functioning, Pediatric Mood Disorders
Brief summary
The study examines actigraphic, observational, psychometric and associated repeated measurements obtained prior to and during psychopharmacological treatment.
Detailed description
Baseline actigraphic measurements, multi-symptom operationally defined observations and psychometric data will be established and repeated to measure treatment response. Additional biological and biometric measures that have potential to further characterize the cohorts under study or treatment response will be collected as practical and when possible.
Interventions
This study will include those anticipating or receiving any pharmacological intervention
Sponsors
Child Psychopharmacology Institute
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
6 Months to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Diagnosis of: * Autism Spectrum Disorder * Mood Disorder * Attention Deficit Hyperactivity Disorder * Unaffected First Degree Relative of Study Subject * Anticipation of pharmacological intervention or current pharmacological intervention
Exclusion criteria
Inability to wear an actigraphy watch
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Actigraphic Measurement | Three week actigraphic measurement periods | Actigraphic measurements are recorded every 30 seconds during three week measurement periods. The actigraphic measurements will be made utilizing an Actiwatch (AW-64 Phillips-Rispironics, Inc.), placed on the subject's non-dominant wrist. The measurements will occur every thirty seconds for approximately 21 consecutive days. Actigraphic measurements collected at this frequency reflect circadian patterns of interest; discern sleep states and characterize activity and activity patterns. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Operationally Defined Observations | Randomly repeated treatment course observational measurements during actigraphic measurement periods | The Systematic Observation Scale™ utilizes operationally defined symptoms that are presented to the primary observer (self or parent) for determination regarding the percentage of time symptoms are present. Target symptoms will be defined at baseline. Systematic Observation Scale measurements will be obtained at baseline and weekly post-treatment for periods defined as treatment initiation, treatment adjustment or treatment-course longitudinal. |
Countries
United States
Outcome results
None listed