Prospective Study on the Incidence of Adrenal Crisis in Patients With Chronic Adrenal Insufficiency

Prospective Cohort-study on the Incidence of Adrenal Crisis in Patients With Chronic Adrenal Insufficiency

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01184209

Enrollment

444

Registered

2010-08-18

Start date

2007-02-28

Completion date

2011-08-31

Last updated

2014-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adrenal Insufficiency

Brief summary

Prospective study to evaluate incidence, causes and potential risk factors for adrenal crisis in patients with chronic adrenal insufficiency.

Detailed description

This is a prospective study following patients with chronic adrenal insufficiency by contacting them every 6 months via questionnaires and telephone. QUestionnaires assess incidence and causes of adrenal crisis, frequency of hospitalization.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* chronic primary or secondary adrenal insufficiency requiring glucocorticoid substitution therapy

Exclusion criteria

* adrenocortical carcinoma * long term glucocorticoid treatment above 7.5 mg prednisone equivalent dose for other reasons than adrenal insufficiency * age \< 18 years

Design outcomes

Primary

Measure	Time frame
incidence of adrenal crisis	during study period

Secondary

Measure	Time frame
mortality	during study period

Other

Measure	Time frame
hospital admission	during study period

Countries

Germany

Outcome results