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Closure of Peritoneum at Cesarean Section and Postoperative Adhesion

Effects of Closure Versus Non-closure of the Visceral and Parietal Peritoneum at Cesarean Section on Adhesions: A Prospective Randomized Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01183000
Acronym
cs adhesions
Enrollment
533
Registered
2010-08-17
Start date
2010-01-16
Completion date
2010-12-31
Last updated
2019-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adhesions, Cesarean Section

Keywords

Formation of adhesions assessed at subsequent cs

Brief summary

Objective: To determine the effect of non-closure of the visceral and parietal peritoneum during Cesarean section on the formation of adhesions. Study design: A prospective randomized trial of 533 women undergoing primary Cesarean section; 256 were randomized to non closure and 277 to closure of the peritoneum. At a subsequent cesarean,he presence of adhesions and their severity was evaluated at several sites: between the layers of the abdominal wall, between the bladder and the abdominal wall, between bladder and uterus, between the uterus and the abdominal wall, and between the bowels and the pelvic organs. A cumulative adhesion score was calculated.

Interventions

PROCEDUREClosure of the peritoneum at cs

Injection of 5 mg Marcaine (anesthetic solution) to the leg

Sponsors

Barzilai Medical Center
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Women undergoing primary CS

Exclusion criteria

* Lack of consent by the patient or an urgent cesarean not allowing time to elicit an informed consent * Previous pelvic or abdominal surgery

Design outcomes

Primary

MeasureTime frame
Adhesion score6 years

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026