Quality of Life in Patients That Undergo J Pouch or Side to End Coloanal Anastomosis for Rectal Cancer

A Randomized, Controlled Trial to Compare the Functional Outcome and Quality of Life in Patients With Low Rectal Cancer Who Undergo a J Pouch or a Side to End Coloanal Anastomosis

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01182116

Enrollment

Registered

2010-08-16

Start date

2009-03-31

Completion date

2016-12-31

Last updated

2018-05-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rectal Cancer

Keywords

J pouch, colorectal, rectal cancer, coloplasty

Brief summary

The investigators hypothesis is that the patients who receive a side to end anastomosis have bowel outcome and quality of life that is equivalent to those who receive a J pouch.

Detailed description

The side to end anastomosis has become popular in recent years as it is technically simple to construct. The difference between the Baker type(side to end) of anastomosis and the J pouch, is that no formal pouch is constructed in the side to end. It has one staple line and the anastomosis. The investigators hypothesis is that the patients who receive a side to end anastomosis have bowel outcome and quality of life that is equivalent to those who receive a J pouch.

Interventions

PROCEDUREJ Pouch

Comparing J pouch, side to end coloanal surgery

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

1. Patients with distal rectal cancers who will be having an abdominal proctocolectomy with a low colorectal anastomosis within 4 cm of the dentate line or a coloanal anastomosis will be candidates for this study. 2. No evidence of distant metastatsis -

Exclusion criteria

Stage IV rectal cancer 1. History of radiation to the pelvis ( eg. for uterine or prostatic cancer) 2. Evidence of synchronus or metachronus disease 3. H/o dementia 4. Prisoners 5. Women who are pregnant 6. History of previous Right Colectomy 7. History of inflammatory bowel disease -

Design outcomes

Primary

Measure	Time frame
Improved function and capacity of the neorectum.	2 years from date of surgery

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026