Amblyopia
Conditions
Keywords
Amblyopia, Retinal layer thickness
Brief summary
The purpose of this study is to examine retinal layer thickness in amblyopia.
Detailed description
Amblyopia is a visual disorder characterized by a reduction of vision that cannot be immediately improved by refractive correction or accounted for by clinically determined anatomic defects of the eye or visual pathway. Evidence for direct retinal changes in eyes with amblyopia has been controversial. It has been hypothesized that amblyopia may affect the postnatal maturation of the retina including the postnatal reduction of retinal ganglion cells. However, although some studies have found incrased retinal nerve fiber layer thickness in amblyopic eyes, others have found no significant differences. This sutdy will examine the retinal layer thickness in amblyopia and compare the retinal layer thickness between amblyopic eyes and nonamblyopic fellow eyes.
Interventions
OTHEROptical coherence tomography
Spectral domain optical coherence tomography will be conducted once when patients are enrolled.
Sponsors
Samsung Medical Center
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
4 Years to 19 Years
Healthy volunteers
No
Inclusion criteria
* Amblyopia
Exclusion criteria
* Other retinal disease * Anisometropia * Neurologic abnormalities
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Retinal layer thickness | One month | Optical coherence tomography scan will be conducted to analyze retinal layer thickness, when the patient are enrolled. |
Countries
South Korea
Outcome results
None listed