Pain, Postoperative
Conditions
Brief summary
In this consecutive, prospective cohort study trial the investigators evaluate if preoperative pain response upon heat stimulation is predictive for acute and subacute postoperative pain after total knee arthroplasty.
Detailed description
The preoperative heat stimulation consists of short and long tonic heat stimulation. Pain response is evaluated with an electronic visual analog scale. Furthermore the investigators evaluate other factors possibly predictable for acute and subacute postoperative pain after total knee arthroplasty - demographic factors, preoperative pain related factors, psychosocial factors (Hospital Anxiety and Depression Scale and Pain Catastrophizing Scale).
Interventions
PROCEDUREPreoperative heat stimulation
Preoperative short and long tonic heat stimulation
Sponsors
Hvidovre University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Ethnic danes, above 18 years and able to give informed consent scheduled for primary, unilateral total knee arthroplasty.
Exclusion criteria
* Bilateral / revision arthroplasty * Disease affection central or peripheral nerve function * Alcohol and medical abuse * Daily use of opioids or glucocorticoids * Malignancy * BMI \> 40 * Depression * Dementia or other cognitive dysfunction
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cumulated pain (from 0-24 hours after surgery) | 24 hours | Pain during walk 5 m (VAS) |
Secondary
| Measure | Time frame |
|---|---|
| Cumulated pain (from day 1 to day 7 after surgery) | 7 days |
| Pain at day 14 after surgery | 14 days |
| Pain at day 30 after surgery | 30 days |
Countries
Denmark
Outcome results
None listed