Lung Transplantation, Sleep Disordered Breathing
Conditions
Keywords
sleep disordered breathing, lung transplantation
Brief summary
The purpose of the study is to investigate the prevalence, clinical predictors and consequences (effect on survival, chronic rejection) of sleep disordered breathing in lung transplant recipients.
Detailed description
All patients with end-stage respiratory failure who are referred for lung transplantation and are older than 18 years old are enrolled. We collect: * Medical history * Blood pressure * Anthropometrics * Pulmonary function * Arterial blood gas * Questionnaire (QOL, ESS) * Sleep diary * Polysomnography
Interventions
None listed
Sponsors
KU Leuven
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Patients with end-stage respiratory failure who are referred for lung transplantation * Informed consent from patient
Exclusion criteria
* Patients who are declined for lung transplantation * Patients \< 18 years old
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of sleep disordered breathing | 1 month after lung transplantation | Polysomnography will be performed at discharge from the hospital (1 month average) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pulmonary function | 1 year after lung transplantation | Effect of SDB on pulmonary function/BOS |
| Investigate possible relationship between SDB and patient medical history | 1 year after lung transplantation | — |
Countries
Belgium
Contacts
Primary ContactBertien MA Buyse, MD, PhD
Backup ContactDries Testelmans, MD, PhD
Outcome results
None listed