Cardiovascular Diseases
Conditions
Keywords
epidemiological risk, diet, fat intake
Brief summary
Substituting whole milk intake for defatted milk will improve indicators of cardiovascular risk, i.e. total cholesterol, triglycerides, Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL)cholesterol, apolipoproteins: ApoB100, Lp(a) and ApoA in a sample of Mexican children 6-13 years of age.
Detailed description
Double blind trial in 600 children 6-13 years of age residing in 12 boarding schools. Schools will be randomized to distribute three types of milk namely: full fat milk (3% fat), partially defatted milk (2% fat) or defatted milk (1% fat) for 90 days of effective exposure (4 months total duration). Subjects will receive 400 mL of the corresponding milk every day (200 mL breakfast and 200 mL night meal) from Monday through Friday. During week ends they will eat a freely chosen diet at home. Milk intake will be measured every day. Diet by 24 h-recall. will be evaluated every month. Blood samples will be obtained at the beginning and at the end of the intervention.
Interventions
Comparison of three levels of fat content in cow´s milk
Comparison of three levels of fat content in cows' milk
Comparison of three levels of fat content in cow´milk
Sponsors
Study design
Eligibility
Inclusion criteria
* Attending selected boarding schools
Exclusion criteria
* No lactose intolerance
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cardiovascular risk indicators | 4 months | Cardiovascular risk is indicated by several determinations of blood fats namely: Total cholesterol, triglicerides, Low-density lipoprotein (LDL) and High density lipoprotein (HDL) cholesterol, lipoproteins: Apo a1,Apo B100 and Lp(a) |
Countries
Mexico