The Role of Narrow Band Imaging Videobronchoscopy in Lung Cancer

The Diagnostic Yield of Narrow Band Imaging Videobronchoscopy in Lung Cancer

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01178190

Acronym

NBI

Enrollment

101

Registered

2010-08-10

Start date

2009-07-31

Completion date

2010-06-30

Last updated

2010-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Cancer

Keywords

narrow band imaging, malignant lesion, lung cancer, NBI

Brief summary

Narrow band imaging (NBI) videobronchoscopy is an optical technique in which filtered light enhances superficial neoplasm based on their neoangiogenic pattern. The objectives of this study investigate its better diagnostic yield in the assessment of lung cancer than conventional flexible bronchoscopy.

Detailed description

Inspection with high resolution endoscopy was followed by NBI. Detected lesions were biopsied. applied the system of shibuya et al. to analyze and classify vascular patterns by NBI into four categories (spiral and screw pattern, dotted pattern, tortuous pattern, avascular pattern) compared with the known diagnostic yield of conventional white light bronchoscopy, An equivalent or superior result will also significantly impact on patient care This technology could aid not only early-stage lung cancer diagnosis but also more accurate local staging of lung cancer.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

19 Years to No maximum

Healthy volunteers

Inclusion criteria

* endobronchial lesion on chest CT

Exclusion criteria

* Age \< 18 years old * Inability to consent for the study * Inability to tolerate bronchoscopy * Active pulmonary infection (bronchitis, pneumonia) * ST elevation or depression on ECG * Prothrombin time prolongation(\<70%) * platelet \<10,000

Design outcomes

Primary

Measure	Time frame	Description
accuracy of NBI videobronchoscopic biopsy	10-11 months	Define and compare the sensitivity, specificity, positive predictive value, negative predictive value, likelihood ratio and accuriacies for the diagnostic techniques for lung cancer.

Secondary

Measure	Time frame	Description
early cancer lesion detection rate using Shibuya descriptors	10-11 months	Define and compare the sensitivity, specificity, positive predictive value, negative predictive value, likelihood ratio and accuriacies for the diagnostic techniques for early lung cancer.

Countries

South Korea

Outcome results