Preventing Postpartum Depression in African American Home Visiting Clients

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01175603

Enrollment

Registered

2010-08-05

Start date

2009-10-31

Completion date

2010-10-31

Last updated

2016-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Keywords

depression, African American, home visiting, prevention

Brief summary

The goal of this study is to determine whether a 6 week intervention is effective in preventing the worsening of depressive symptoms and development of clinical depression in low-income African American pregnant and recently delivered women who are enrolled in home visiting programs.

Detailed description

This study will conduct a randomized controlled trial (RCT) with women from four Baltimore City home visiting programs. We will screen 200 women who are pregnant or have a child \< 6 months for study inclusion; 91 women at elevated risk for developing postpartum depression (PPD) will be randomized to an intervention (MB Course) or usual home visiting control group. Women in the intervention group will receive the 6-week MB Course delivered in a group setting by the Study Clinician with reinforcing messages provided by home visitors during 1-on-1 home visits, while women in the attention control will receive usual home visiting services and information on postpartum depression. Primary outcomes include depressive symptoms and depressive episodes.

Interventions

BEHAVIORALMothers and Babies Course (Adapted for Baltimore Home Visiting Programs)

6 weekly 2-hour cognitive-behavioral intervention sessions held in group format

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

14 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* pregnant or has child \< 6 months of age * enrolled in home visiting program * exhibiting elevated depressive symptoms and/or personal history of clinical depression

Exclusion criteria

* no current clinical depression at time of enrollment

Design outcomes

Primary

Measure	Time frame
Depressive symptoms	Baseline
Depressive Symptoms	3 months post-intervention

Secondary

Measure	Time frame
Depressive episodes	3 months post-intervention
Depressive Episodes	6 Months Post-Intervention

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026