Endometrial Ablation With Non-hysteroscopic Methods

Treatment of Dysfunctional Uterine Bleeding With Second Generation Ablation Devices: Microwaves (MEA®) vs Bipolar Impedance Control System (Novasure®)

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01173965

Enrollment

Registered

2010-08-03

Start date

2008-01-31

Completion date

2011-02-28

Last updated

2012-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dysfunctional Uterine Bleeding

Brief summary

Endometrial ablation in women with dysfunctional uterine bleeding using second generation ablation devices is a common widespread therapeutic approach. This study aims to prove that amenorrhoea rates using Novasure are higher than those observed in microwave endometrial ablation, one year following intervention.

Interventions

DEVICEMEA

Microwave endometrial ablation device

DEVICENovasure

Bipolar impedence control system

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

30 Years to 49 Years

Healthy volunteers

Inclusion criteria

* Women presenting with dysfunctional uterine bleeding having completed their family planning(no wish for further childbearing)

Exclusion criteria

* Endometrial pathology * FSH \> 20 day 2 -day 3 of the cycle * Clotting Disorders * Thyroid Dysfunction

Design outcomes

Primary

Measure	Time frame
Amenorrhoea rates one year after intervention	—

Countries

Greece

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026