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Effects of Pursed-lip Breathing on Exercise Tolerance and Dynamic Hyperinflation in COPD

Effects of Pursed-lip Breathing on Exercise Tolerance and Dynamic Hyperinflation in Chronic Obstructive Pulmonary Disease

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01173328
Enrollment
40
Registered
2010-08-02
Start date
2007-03-31
Completion date
2009-10-31
Last updated
2010-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease

Keywords

exercise tolerance, dynamic hyperinflation, respiratory mechanics

Brief summary

Pursed-lip breathing (PLB) has been advocated to reduce respiratory rate and improve oxygen saturation in patients with chronic obstructive pulmonary disease (COPD) at rest. Although PLB is a strategy that potentially reduces expiratory flow limitation, there are only few studies addressing its effects on exercise. This study aimed to assess the ability of PLB to change the breathing pattern, degree of dynamic hyperinflation (DH) and arterial oxygenation in COPD patients during exercise. Exercise tolerance was evaluated by endurance time and respiratory mechanics was evaluated by forced oscillation technique.

Interventions

Pursed-lip breathing involves a nasal inspiration followed by expiratory blowing against partially closed lips, avoiding forceful exhalation.

Sponsors

Universidade Federal do Rio de Janeiro
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
40 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Clinical diagnosis of chronic obstructive pulmonary disease (COPD) * Regular treatment at Clementino Fraga Filho University Hospital (UFRJ)

Exclusion criteria

* Exacerbation in the preceding 4 weeks * SpO2\<85% at peak exercise * Other diseases that may contribute to dyspnea and exercise intolerance

Design outcomes

Primary

MeasureTime frame
Endurance timewithin the first 01 hour

Secondary

MeasureTime frame
inspiratory capacitywithin the first 01 hour
oxygen saturationwithin the first 01 hour
dyspneawithin the first 01 hour
forced oscillation variableswithin the first 01 hour

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026