Persistence of Rabies Antibody 1-5 Years After the Post-exposure Prophylaxis With Vero Cell Antirabies Vaccine and Antibody Response to a Single Booster Dose

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01173302

Enrollment

160

Registered

2010-08-02

Start date

2010-05-31

Completion date

2010-09-30

Last updated

2010-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rabies

Keywords

Rabies, Anti-rabies antibody, Persistence

Brief summary

This study is to investigate the persistence of rabies Chinese manufactured antibody 1-5 years after the post-exposure prophylaxis with vero cell antirabies vaccine and antibody response to a single booster dose. A total of 160 subjects would be enrolled. These subjects were all administered ChengDa antirabies vaccine from 2005 to 2009. After informed consent is obtained, these subjects would be tested for their antirabies antibody titer and given a single booster dose. Seven and 14 days later, the investigators would re-evaluate the antibody titer.

Interventions

BIOLOGICALRabies vaccine, manufactured by ChengDa

1 dose before the antibody is tested

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

20 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* 20 to 60 years old * Healthy * Given ChengDa rabies vaccine * Good compliance * Obtained informed consent

Exclusion criteria

* Other than inclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
Rabies antibody titer	6 months	We test the antirabies antibody titer before and after the single booster dose

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026