Hematological Malignancies
Conditions
Keywords
Leukemia, Lymphoma, Bone-Marrow Transplant, Neutropenia, Acute respiratory failure, Mechanical ventilation, Post ICU burden, ICU triage, Dialysis, Septic shock
Brief summary
The purpose of this study is to determine: * Condition of intensive care unit (ICU) admission in patients with haematological malignancies. * ICU hospital and up to one year mortality. * Assessment of post ICU burden and health related quality at 90-d and 1 year.
Detailed description
1. To identify prognostic factors of short and medium term mortality, by underlining the respective weights of organ dysfunction and characteristics of underlined malignancy 2. Evaluate the health related quality of life of intensive care survivors(SF36) 3. Impact of intensive care on families burden (HADS, IES). 4. Assess clinicians' satisfaction ( intensivists, haematologists and intensive care nurses) in relation to medical decision-making. 5. Establish the relevance of antifungal treatments.
Interventions
None listed
Sponsors
Assistance Publique - Hôpitaux de Paris
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Hematological malignancies * hospitalization in ICU * age \>= 18 years
Exclusion criteria
* Patients who have already participated to TRIAL-OH
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Survival status at one year | 1 year | survival status (alive or death) at one year |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Health related quality of life of patients and their relatives | day 90 and 1 year | — |
| ICU mortality | 1 week (estimated mean time until ICU discharge) | survival status at ICU discharge |
| Survival status | day 90 | — |
| Hospital mortality | 3 weeks (estimated mean time until Hospital discharge) | survival status at hospital discharge |
Countries
France
Outcome results
None listed