Use of Laser Speckle to Study Post Occlusive Reactive Hyperhemia in Healthy Subjects

Evaluation Chez Des Sujets Volontaires Sains de l'ischémie-reperfusion cutanée

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01169974

Acronym

SpeckleShake

Enrollment

Registered

2010-07-26

Start date

2011-02-01

Completion date

2012-12-04

Last updated

2017-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Microcirculation

Keywords

Microcirculation, laser flowmetry, Skin, Physiology

Brief summary

The investigators aim to test the hypothesis that Laser speckle contrast imaging allows for the measurement of cutaneous blood flow following various durations of tourniquet ischemia.

Detailed description

Ischemia and post occlusive reactive hyperemia in the skin is tested in healthy normal subjects for tourniquet ischemias of 1, 2 & 3 minutes at rest.

Interventions

OTHERtourniquet ischemia

Recording of cutaneous blood flow on the forearm at rest before and following tourniquet ischemias of 1 , 2 & 3 minutes

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Healthy volunteers * Affiliation to the French health system

Exclusion criteria

* Any disease or chronic treatment

Design outcomes

Primary

Measure	Time frame	Description
Laser speckle	with 2 minutes of ischemia	Peak value of laser speckle signal

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026