Corneal Epithelial Defect
Conditions
Brief summary
80 diabetic patients underwent vitrectomy and had no history of Eye herpes infection, Refractive surgery, Autoimmune disease, Immune deficiency will be randomized into two groups (double blind)to evaluate the role of umbilical cord serum therapy on improvement of corneal epithelial defect following diabetic vitrectomy. Both groups will take the conventional medication including Chloramphenicol, Betamethasone, Cycloplegic eye drops besides the case group will take umbilical cord serum eye drop in the eye operated. After surgery the corneal epithelial defect will be measured by slit lamp.
Interventions
DRUGconventional therapy plus umbilical cord serum eye drop
chloramphenicol and betamethasone eye drops every 6 hours, cycloplegic (homatropine) eye drop every 8 hours plus umbilical cord serum eye drop 20% every 4 hours
DRUGconventional therapy
chloramphenicol and betamethasone eye drops every 6 hours, cycloplegic (homatropine) eye drop every 8 hours
Sponsors
Ophthalmic Research Center
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Diabetic patients with corneal epithelial defect following diabetic vitrectomy at labbafinejad Hospital
Exclusion criteria
* Any history of Eye herpes infection, Refractive surgery, Autoimmune disease, Immune deficiency * Patients with one eye * Use of any eye drops except Chloramphenicol, Betamethasone, Cycloplegic and contact lens for corneal epithelial defect
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measurement of corneal epithelial defect | — | measurement of corneal epithelial defect in days 3,5,7,12 by slit lamp |
Countries
Iran
Outcome results
None listed