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Frequency of Axial Spondyloarthropathy Among Patients Suffering From Fibromyalgia

Frequency of Axial Spondyloarthropathy Among Patients Suffering From Fibromyalgia - Application of the ASAS Classification Criteria

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01167413
Enrollment
100
Registered
2010-07-22
Start date
2010-08-31
Completion date
2011-01-31
Last updated
2010-08-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ankylosing Spondylitis, Fibromyalgia

Brief summary

Fibromyalgia Syndrome (FMS) is a non - inflammatory condition characterized by the presence of chronic, widespread musculoskeletal pain and tenderness; FMS is considered to be the result of increased processing of pain by the central nervous system. Axial spondyloarthropathy is the hallmark of Ankylosing Spondylitis (AS), an inflammatory joint disease involving the axial spine, the sacroiliac joints as well as peripheral joints. Although FMS and AS differ vastly in their pathogenesis, a considerable clinical overlap may exist between these conditions. Both disorders typically cause chronic nocturnal back pain and disturbed sleep may accompany either condition. In addition,the investigators have previously described an increased prevalence of (secondary) FMS among female AS patients. This overlap may have important clinical implications since the presence of comorbid FMS may lead to increased severity results on commonly used instruments in the evaluation of disease activity in AS, such as the BASDAI and BASFI . Recently, the Assessment of Spondyloarthritis international Society (ASAS) has published updated classification criteria for axial spondyloarthropathy. These criteria, which are summarized in table 1, are based on the evaluation of patients suffering from chronic back pain with an age of onset of less than 45. Objective: The objective of the current study is to evaluate the prevalence of axial spondyloarthropathies among FMS patients, utilizing the new ASAS criteria.

Interventions

DEVICEEvaluation by manual Dolorimeter

Patients will be examined by a manual Dolorimeter

OTHERSIJ imaging

Patients will undergo imaging of the Sacroiliac joint by plain x-ray or MRI and sacroileitis will be documented

Sponsors

Tel-Aviv Sourasky Medical Center
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients fulfilling American College of Rheumatology criteria for classification of Fibromyalgia: * Widespread pain lasting over three months * Tenderness in at least 11 of 18 points

Exclusion criteria

* Patients with known inflammatory joint disease prior to the study * Patient not able to give informed consent * Pregnant women

Design outcomes

Primary

MeasureTime frame
Prevalence of Ankylosing Spondylitis as diagnosed according to ASAS criteria1 month

Contacts

Primary ContactJacob N Ablin, MD
ajacob@post.tau.ac.il972-3-6973668

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026