Healthy, Overweight, Obesity
Conditions
Keywords
Healthy adults with BMI over 25.0 kg/m2
Brief summary
The purpose of this study is to determine whether astaxanthin (ASX) supplementation will reduce obesity-induced oxidative stress and improve lipid profile in overweight and obese adults.
Interventions
DIETARY_SUPPLEMENTastaxanthin
astaxanthin 20mg for 12 weeks
Sponsors
Ministry of Health & Welfare, Korea
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
SINGLE
Eligibility
Sex/Gender
ALL
Age
19 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* Subjects with BMI over 25.0 kg/m2 * Non-smoker
Exclusion criteria
* Excessive alcohol consumption * Pregnant or lactating women * Dyslipidemia, hyperglycemia, or other chronic diseases. * Subjects who were taking vitamin supplements
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluation of the plasma MDA (malonaldehyde) level | 12 weeks | MDA is a three chain aldehyde produced during the composition of a lipid hydroperoxide and is a well known indicator of lipid peroxidation. The purpose of this stduy is to determine whether ASX supplementation lowers oxidative stress using MDA,a biomarker. |
Countries
South Korea
Contacts
Primary ContactYeo-kyu Youn, Doctor
Outcome results
None listed