Age-Related Macular Degeneration
Conditions
Keywords
AMD, Cataract surgery, Size of AMD, Influence of cataract surgery on AMD Size
Brief summary
The purpose of this study was to find out if in patients with non-exudative age-related macular degeneration (AMD), randomly assigned to cataract surgery, any AMD size progression or progression to exudative AMD could be detected 6 months after surgery.
Interventions
PROCEDURECataract Surgery
Fifty-four patients with cataract and non-exudative age-related macular degeneration (AMD) were randomized into an early surgery group (ES=28) with immediate cataract surgery and a control group (CO=26) where surgery was performed after six months.
Sponsors
Medical Scientific Fund of the Mayor of Vienna
The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patients with cataract and non-exudative age-related macular degeneration
Exclusion criteria
* Patients with retinal pathologies other than AMD, exudative AMD, progressive glaucoma, myopia \> 10 diopters, panretinal laser treatment, former cataract or vitreoretinal surgery, were excluded.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| AMD size (defined central region of interest) | at enrollment, after 6 months | To evaluate AMD size progression, absolute and relative differences in pixels of the ROI were cal-culated by equivalent tests. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Functional ophthalmic assessments | at enrollment, after 6 months | Cataract grade (LOCS-III), Visual acuity (distance/near), contrast acuity tests, Visual Function Index (VF-14) |
Countries
Austria
Outcome results
None listed