Aneuploidy Rate
Conditions
Brief summary
Several stimulation protocols have been used in in vitro fertilization (IVF) in a cycle of egg donation; recombinant FSH and human FSH are included. The effect of each kind of hormone on aneuploidy rate it is unknown. If there was an increase on aneuploidy rate of one of these stimulation protocols, there will be a negative effect on the successful rates in the egg donation cycles. The aim of this study is to observe if there is a different in aneuploidy rate and morphological oocyte parameters between different stimulation protocols.
Interventions
PROCEDUREStimulation with human FSH
Human FSH
PROCEDUREStimulation with recombinant FSH
Recombinant FSH
Sponsors
IVI Madrid
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* Egg donation cycles with more than 8MII in oocyte retrieval day
Exclusion criteria
* Male factor * Uterine malformations * genetic alterations
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Aneuploidy Rate | 2011 January | Analysis of all nuclei fixed |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Oocyte morphology | 2011 january | Analysis of all oocytes |
| Outcome rates (implantation, pregnancy and miscarriage rate) | 2011 April | Time requierd to know all the implantation, pregnancy and miscarriage rate |
Countries
Spain
Outcome results
None listed