Breast Cancer, Sentinel Node
Conditions
Brief summary
Rationale: Like in primary breast cancer, prognosis in recurrent breast cancer is correlated with regional lymph node status. Therefore, axillary staging may be warranted in patients with recurrent disease and intact axillary nodes, although this has not been described in guidelines yet. The lymphatic drainage pathways in the breast and/or axilla could have been changed due to prior surgery and/or radiotherapy. These aberrant drainage pathways could be detected with lymphatic mapping and sentinel node biopsy (SNB), leading to a more accurate staging. Objective: To assess the technical feasibility of lymphoscintigraphy after prior breast surgery. A second goal is to investigate whether or not previous breast surgery (with or without radiotherapy) significantly changes the lymphatic drainage pathways of the breast.
Interventions
RADIATIONLymphoscintigraphy
in all women a lymphoscintigraphy was done to investigate drainage patterns of a previous operated breast and axilla
Sponsors
Catharina Ziekenhuis Eindhoven
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Inclusion criteria
* treatment with BCT with SNB and/or ALND for primary breast cancer * previous primary breast cancer located in the upper-outer quadrant of one breast * Primary breast cancer treatment at least 3 years before the analysis, with or without adjuvant chemo- or hormonal therapy.
Exclusion criteria
* breast surgery for other reasons than breast cancer * recurrent breast cancer * former allergic reaction to 99mTc-colloidal albumin.
Countries
Netherlands
Outcome results
None listed