Creatine Supplementation and Bone Mass

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01163370

Enrollment

Registered

2010-07-15

Start date

2010-07-31

Completion date

2011-08-31

Last updated

2011-11-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteopenia, Osteoporosis

Keywords

creatine supplementation, resistance training, osteopenia, osteoporosis, bone mineral density

Brief summary

Resistance training as well as creatine supplementation may increase bone mass. Therefore, the investigators speculate that resistance training combined with creatine supplementation would promote additive benefits on bone mass in elderly women with osteopenia and osteoporosis.

Interventions

DIETARY_SUPPLEMENTcreatine supplementation

20g/d for 7 days followed by 5g/d for 23 weeks

OTHERexercise training

resistance training twice a week for 24 weeks

OTHERplacebo (dextrose)

20g/d for 7 days followed by 5g/d for 23 weeks

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

FEMALE

Age

60 Years to No maximum

Healthy volunteers

Inclusion criteria

* osteopenia and osteoporosis * women older than 60 years old

Exclusion criteria

* cardiovascular diseases or muscular disturbances precluding exercise training * drugs affecting bone metabolism

Design outcomes

Primary

Measure	Time frame
bone mineral density	six months

Secondary

Measure	Time frame	Description
cognition	six months	—
physical capacity	six months	including muscle strength, balance and muscle function

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026