Role of Sphingolipids in Pulmonary Edema

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01162161

Acronym

09-045

Enrollment

Registered

2010-07-14

Start date

2010-07-31

Completion date

2013-05-31

Last updated

2015-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Edema

Keywords

sphingolipid, ceramide, sphingomyelinase

Brief summary

In this mono-center prospective study, the impact of changes in the sphingolipid metabolism in patients with pulmonary edema will be investigated.

Detailed description

There will be three groups of patients: 1. hydrostatic pulmonary edema 2. toxic pulmonary edema 3. not ventilated patients without any pulmonary edema Samples of a routine bronchoalveolar lavage and EDTA-blood will be analysed in respect of sphingolipids, ceramide, sphingomyelin-phosphodiesterase and several cytokines.

Interventions

None listed

Study design

Observational model

CASE_CROSSOVER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* above the age of 18

Exclusion criteria

* taking steroids

Countries

Germany

Outcome results