Nutritional Status Among Older Adults. Risk Factors and Consequences of Malnutrition

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01161342

Enrollment

1771

Registered

2010-07-13

Start date

2008-03-31

Completion date

2009-05-31

Last updated

2015-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malnutrition

Keywords

Malnutrition, Aged, Aged 80 and over, Prevalence, Mortality

Brief summary

The aim of the study is to estimate the prevalence of malnutrition among older adults admitted to hospital and to analyse predictive factors for malnutrition. Further, the aim was to analyse the association between nutritional status and all-cause and cause-specific mortality. The hypothesis is that malnourished patients have a higher mortality then well-nourished patients after three years.

Detailed description

The baseline survey was a cross-sectional study of 1771 patients aged ≥65 years who were admitted to hospital. Nutritional status was assessed using the MNA instrument, and possible risk factors associated with malnutrition were recorded during the hospital stay. All-cause mortality was followed up after median 3.5 years s in a cohort study of 1767 participants. Cause-specific mortality was followed up after median 4.7 years in a cohort of 1767 participants. Previous dietary intake in middle-aged and older adults was recorded at basline in 725 participants, who had their nutritional status assessed with the MNA when admitted to hospital 10 years later.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients 65 years or older

Exclusion criteria

* unable to communicate and no relative could anwer the questions (n = 356) * receiving palliative care (n = 44) * impossible to measure height or weight (n = 22) * miscellanious (n = 71)

Design outcomes

Primary

Measure	Time frame	Description
Nutritional status according to the screening instrument Mini Nutritional Assessment (MNA)	30 minutes	\[The 18 questions in the MNA instrument are weighted, and the threshold values of the instrument categorize patients into three nutritional status groups: well-nourished (MNA score 24-30), at risk of malnutrition (MNA score 17-23.5), or malnourished (MNA score \<17).
All-cause mortality	All-cause mortality was analyzed after median 3.5 years.	Survival was calculated from the date of the MNA screening to the date of death.
Cause-specific mortality	Cause-specific mortality was analyzed after median 4.7 years.	Survival was calculated from the date of the MNA screening to the date of cause-specific death.

Outcome results