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Genes and Phenotype (GAP) A National Resource for Genotype-Phenotype Studies of Immunological and Inflammatory Pathways

Genes and Phenotype (GAP) A National Resource for Genotype-Phenotype Studies of Immunological and Inflammatory Pathways

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01161056
Acronym
GAP
Enrollment
5000
Registered
2010-07-13
Start date
2009-05-31
Completion date
2015-04-30
Last updated
2015-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Immune System Diseases

Brief summary

The purpose of this study is to enrol generally healthy adults, who are asked to provide a blood sample, to study how the immune system works.

Detailed description

The primary purpose of this research is to develop a better understanding of how the immune system works. By studying immune function in many people, we will be able to determine the range of normal variation. The second purpose is to enroll people who are willing to serve as comparisons in future research studies into the Genotype and Phenotype Research Registry (GAP Registry). Volunteers are asked to provide information on age, ethnicity and medical history. Volunteers are asked to provide a blood sample of up to 100cc and allow us to contact you about additional studies.

Interventions

None listed

Sponsors

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
CollaboratorNIH
University of Alabama at Birmingham
CollaboratorOTHER
Northwell Health
Lead SponsorOTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Over age 18 * Generally healthy

Exclusion criteria

* History of autoimmune disease * History of chronic immunodeficiency or chronic viral infections such as Epstein Barr virus, hepatitis or HIV * Currently undergoing treatment for cancer * Current treatment with immuno-suppressant drugs * Pregnancy

Design outcomes

Primary

MeasureTime frameDescription
Number of healthy participants enrolled5 yearsThis is a registry to enroll healthy individuals who are interested in being contacted about research studies they can participate in as a healthy control

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026