Optimal Site of Administration for Continuous Wound Infusion After Cesarean Section

Evaluation of Optimal Anatomical Layer for Continuous Wound Infusion of Local Anesthetics Combined With NSAIDs Through a Multiorifice Catheter for Postoperative Pain Intensity After Elective Cesarean Delivery

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01160913

Enrollment

Registered

2010-07-13

Start date

2007-10-31

Completion date

2008-12-31

Last updated

2010-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean Section

Brief summary

The purpose of this randomized double-blind study is to evaluate in which anatomical layer (AF versus BF) continuous wound infusion of local anesthetics combined with NSAIDs through a multiorifice catheter has the best effectiveness during the first 48 hours on postoperative pain intensity after elective cesarean delivery.

Interventions

PROCEDUREContinuous wound infusion

PROCEDUREContinuous wound

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* elective Cesarean Section under spinal anesthesia over37 weeks' gestation

Exclusion criteria

* allergy to NSAIDs * ASA III or higher * refusal to participate

Design outcomes

Primary

Measure	Time frame
Cumulative intravenous morphine consumption	48 hours

Secondary

Measure	Time frame
Postoperative pain intensity at rest and mobilization	admission, 3,6,12,24,36,48h
adverse effects (nausea, vomiting, itching, sedation)	—

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 30, 2026