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Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Ethiopia

Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Southern Ethiopia: a Cluster-randomized Controlled Trial

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01160809
Enrollment
6082
Registered
2010-07-12
Start date
2008-09-30
Completion date
2009-01-31
Last updated
2010-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Long Lasting Insecticidal Nets, Malaria, Mosquito Repellent

Keywords

Malaria, Mosquito repellent, LLINs

Brief summary

The combined use of a mosquito repellent and long lasting insecticidal nets (LLINs) by household members would result in a 40% reduction in malaria prevalence compared with households that only use LLINs.

Detailed description

It has been recognized that the use of malaria preventive measures in combination with LLINs could improve the effectiveness of nets in preventing the disease. This study examined the effect of a combined use of mosquito repellent (i.e., Buzz Off) and LLINs on malaria prevalence in an area of unstable and seasonal malaria transmission.

Interventions

OTHERMosquito repellent

Mosquito repellent (Buzz Off jelly) every evening applied to face, neck, hands and legs

Sponsors

Addis Ababa University
CollaboratorOTHER
Columbia University
CollaboratorOTHER
Coalition Against Malaria in Ethiopia
CollaboratorUNKNOWN
Malaria Consortium, Ethiopia
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* All volunteer household members

Exclusion criteria

* Infants less than two months * Not in the study area

Design outcomes

Primary

MeasureTime frameDescription
Malaria parasite (P. falciparum and/or P. vivax)through microscopic detectionThe objective of the study is to investigate the impact of a combined use of mosquito repellent and LLINs in reducing malaria. The primary outcome of the study is detection of malaria parasites (P. falciparum and/or P. vivax) through examination of microscopic blood slides collected from finger-pricks.

Secondary

MeasureTime frameDescription
Household ownership and utilization of LLINsOwneship and utilization of LLINs by household members during the night before the baseline survey

Countries

Ethiopia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 8, 2026