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Genetic Contributions to Autism Spectrum Disorders

Genetic Contributions to Autism Spectrum Disorders

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01160783
Enrollment
240
Registered
2010-07-12
Start date
2007-04-01
Completion date
2030-02-01
Last updated
2026-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asperger's Syndrome, Autism, Autism Spectrum Disorder, Pervasive Developmental Disorder

Keywords

Autism, Asperger's Syndrome, Asperger Syndrome, Autistic Disorder, Autism Spectrum Disorder, Pervasive Developmental Disorders, Pervasive Developmental Disorder-Not Otherwise Specified, Child Development Disorders, Pervasive, PDD-Not Otherwise Specified

Brief summary

This study is working towards gaining a better understanding of the genetic and environmental factors involved in autism spectrum disorders (ASD), which includes autism, pervasive developmental disorder (PDD), and Asperger's syndrome. The investigators hope that information gained from this study will lead to new ways of diagnosing and treating ASDs.

Detailed description

Participation generally takes less than 2 hours to complete and travel to Children's Hospital Boston is not required. Participants are asked some questions about their medical and family history. The investigators also request permission to review medical records related to the autism spectrum disorders (ASD) diagnosis. Finally, the investigators obtain a small blood or saliva sample in order to search for genes that may be important in understanding ASD. The investigators can arrange for the blood draw through a participant's physician or a clinical laboratory and saliva samples can be obtained through the mail. The study questions are answered via telephone or mailed questionnaires. There is no cost to participate.

Interventions

None listed

Sponsors

Boston Children's Hospital
Lead SponsorOTHER

Study design

Observational model
FAMILY_BASED
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Months to No maximum
Healthy volunteers
No

Inclusion criteria

* Clinical diagnosis of an Autism Spectrum Disorder (autism, pervasive developmental disorder (PDD), or Asperger's syndrome) * Age \> 18 months

Exclusion criteria

* Do not have the diagnosis of an ASD * Participation in the "Phenotypic and Genetic Risk Factors in ASD" study at Boston Children's Hospital.

Design outcomes

Primary

MeasureTime frameDescription
Gene expression levelsAt sample collectionGene expression levels

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORChristopher Walsh, MD, PhD

Boston Children's Hospital

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 19, 2026