Meta-analysis of Efficacy of Topotecan

Meta-analysis of Efficacy of Topotecan and Other Treatments for Recurrent Carcinoma of the Cervix

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01160185

Enrollment

Registered

2010-07-12

Start date

2009-06-30

Completion date

2009-07-31

Last updated

2010-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Intraepithelial Neoplasia

Brief summary

This meta-analysis was conducted to investigate the efficacy of Topotecan and other treatments for recurrent and stage IVB carcinoma of the cervix

Detailed description

Studies included in the meta-analysis were: GOG-0179, GOG-0204 & GOG-0169

Interventions

DRUGpaclitaxel

paclitacel

DRUGcisplatin

cisplatin monotherapy

DRUGtopotecan

topotecan

Study design

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

21 Years to No maximum

Healthy volunteers

Inclusion criteria

* Randomised Clinical Trials or systematic reviews or meta-analyses * Treatment with topotecan or platinum-based single and combination regimens in female patients of any race with cancer of the cervix recurrent after radiotherapy or stage IVB disease

Exclusion criteria

* None

Design outcomes

Primary

Measure	Time frame
Survival	12 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026