Gastrointestinal Motility
Conditions
Keywords
Endoscopy, Video Capsule, Motility, Gastrointestinal
Brief summary
The purpose of this study is to evaluate the clinical usefulness of a capsule (SmartPill\ ) measuring pH, pressure and temperature from within the entire GI tract to determine gastric emptying time, combined small and large bowel transit time and total transit time. In addition, the Capsule will characterize pressure patterns and provide motility indices for the antrum and duodenum. It is believed that the condition of your digestive system can have a large impact on your overall physical health. Therefore,the investigators would like to assess whether using the pill device helps to determine any functional problems in patients in the ICU. The investigators are studying ICU patients because any change in their condition can have a large impact on their recovery.
Interventions
DEVICESmartPill
Qualifying patients were assigned to the study within four days of hospital admission. They all received a gastro-duodenal tube and capsule. The motility capsule (SmartPill®) was placed into the capsule delivery device (AdvanCE™, US Endoscopy) and advanced blindly into the stomach and released
Sponsors
University of Louisville
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* suffered from traumatic or non-traumatic intracranial hemorrhage and were admitted to an intensive care unit (ICU) at University of Louisville Hospital * sedated and had tracheal intubation and mechanical ventilation * older than 18 years
Exclusion criteria
* younger than 18 years * multiple injuries, especially abdominal trauma or inflammatory bowel disease * history of complicated abdominal surgery or unknown type of abdominal surgery * clinical evidence of ileus or suspected bowel obstruction * a pacemaker
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Transit time | 5 days | The subjects were followed from the time of placement of the capsule in the stomach until the capsule was viewed in the stool or abdominal X-rays revealed it had passed from the body |
Countries
United States
Outcome results
None listed