Elderly, Growth Hormone
Conditions
Brief summary
Tendon and ligament injuries are a frequent problem among athletes but also in the general population. The healing process is a prolonged process, and complete recovery of tissue strength is nearly never reached. The purpose of this study is to examine the effect of local injection of human Growth Hormone on tendon collagen synthesis.
Detailed description
Tendon and ligament injuries are a frequent problem among athletes but also in the general population. The healing process is a prolonged process, and complete recovery of tissue strength is nearly never reached. The purpose of this study is to examine the effect of local injection of human Growth Hormone on tendon collagen synthesis. in order to investigate the collagen synthesis potential and the influence of growth hormone, 12 elderly males age \> 50 year, is enrolled in this study.
Interventions
DRUGGrowth Hormone
infusion of Growth hormone in the patella tendon.
Sponsors
Bispebjerg Hospital
University of Aarhus
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
MALE
Age
55 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* BMI 18.5 - 25.0
Exclusion criteria
* earlier knee injury
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| • Fraktionele collagen protein synthesis in human patella tendon | 01122010 |
Countries
Denmark
Outcome results
None listed