Clinical Significance of Retinal Emboli During Diagnostic and Therapeutic Cardiac Catheterization

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01157338

Enrollment

300

Registered

2010-07-07

Start date

2009-10-31

Completion date

2010-05-31

Last updated

2010-07-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Catheterization, Embolism, Retina

Keywords

Catheter, coronary artery disease, embolus, stroke, retinal emboli

Brief summary

Retinal emboli is a common phenomenon in cardiac catheterization. In this study the investigators evaluate the incidence of retinal emboli post diagnostic and therapeutic cardiac catheterization over 300 patients. The incidence was 6.3% and had no clinical sequel on visual acuity and visual field.

Detailed description

Background and Purpose Cardiac catheterization may cause retinal embolization, a risk factor for cerebrovascular emboli and stroke. We describe the incidence of clinically silent and apparent retinal emboli following diagnostic and interventional coronary catheterization and associated risk factors. Methods Three hundred selected patients attending a tertiary referral center for diagnostic and therapeutic cardiac catheterization were studied. Direct retinal examination and examination of the visual field and acuity were done before and after catheterization by a retinal specialist.

Interventions

PROCEDUREdiagnostic cardiac catheterization

coronary intervention: angiography

PROCEDUREtherapeutic cardiac catheterization

cardiac catheterization: angioplasty

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

52 Years to 68 Years

Healthy volunteers

Inclusion criteria

* every patient with diagnostic and therapeutic cardiac catheterization

Exclusion criteria

* patient refusal to follow up ophthalmology * abscence of coronary disease in angiogram * abnormal retinal angiogram prior to study

Design outcomes

Primary

Measure	Time frame	Description
retinal emboli	—	retinal emboli detected by retinal especialist by direct examination

Secondary

Measure	Time frame	Description
visual field	—	visual field detected by ophthalmologist
visual acuity	—	snellen chart by ophthalmologist

Countries

Iran

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026