Labor
Conditions
Keywords
Epidural analgesia, Latent analgesia, Active analgesia, Cesarean section
Brief summary
Currently, it is certain that neuraxial analgesia in early stage of labor and delivery dose not increase the risk of Cesarean section. However, given ethical reasons, whether such a medical procedure could increase the Cesarean rate compared with those who did not received neuraxial analgesia or not is yet to be known. It is difficult to perform such a study in occidental countries because they have a higher rate of labor analgesia. On the contrary, the rate of labor analgesia in China is up to date only 1%, so it can be done easily. The investigators hypothesized that no neuraxial analgesia itself were a risk factor to Cesarean section. Therefore, the investigators design this study to compared the effect of neuraxial analgesia on the rate of Cesarean delivery with those who did not received neuraxial analgesia.
Interventions
PROCEDURENeuraxial analgesia
Neuraxial analgesia will be given at any time if the parturient requested analgesia
PROCEDURENon-neuraxial analgesia
No neuraxial analgesia will be given to those who will not want to an analgesia
Sponsors
Nanjing Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
19 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Age \>= 19yr, \<=40 yr * Height 140 - 170 cm * Singleton pregnancy * Uncomplicated pregnancy * Chinese
Exclusion criteria
* Multiple gestations * Pregnancy-induced hypertension * Diabetes mellitus * Chronic pain * Allergic to opioids and/or local anesthetics * Failed to performing inter lumbar space catheterization * Organic dysfunction * Contraindications for neuraxial analgesia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cesarean rate | One day after birth | Rate of Cesarean delivery in both neuraxial and non-neuraxial analgesia women |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Instrumental delivery | One day after birth | The rate of instrument-assisted delivery in both neuraxial and non-neuraxial analgesia women |
| VAS pain intensity | At the begining of labor (0 min) | Labor pain intensity assessed using visual analog scale (VAS) |
| Time of successful labor | From the initial of labor (0 min) to completion of delivery (this is changable individually) | Labor duration in both neuraxial and non-neuraxial analgesia women |
| Time of second stage of labor | From the cervix at 10 cm to successful delivery of the baby (this is changable individually) | Duration of the second stage of labor |
| Overall feeling of satisfaction of the labor | At the end of successful baby delivery (it is changable individually) | Satisfaction assessed using a visual analog scale (VAS) at the end of the labor delivery |
| Side effects | From the initial of labor (0 min) to the end of the labor (is is changable individually) | Side effects recorded from the labor initiation to successful delivery |
| Time of the first stage of labor | From initial of the labor to the cervix reached to 10 cm (Different in different patients) | Duration of the first stage of labor |
Countries
China
Outcome results
None listed