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Interventions to Decrease the Impact of Post-OPerative Ileus After Liver Transplant or Resection Surgery

Interventions to Decrease the Impact of Post-Operative Ileus After Liver Transplant or Resection Surgery

Status
Completed
Phases
Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01156129
Enrollment
111
Registered
2010-07-02
Start date
2010-09-01
Completion date
2012-12-01
Last updated
2023-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ileus

Keywords

liver transplant, liver resection

Brief summary

This is a randomized controlled trial to assess ways to address post-operative ileus (POI) in adult patients on the liver transplant service undergoing either liver transplant or resection surgery. Patient who speak and understand English will be randomized into one of three groups including a.)control group receiving standard therapy for post-operative ileus, b.)group receiving standard therapy and acupressure bracelets, and c.)group receiving standard therapy and sugar free gum four times daily.

Detailed description

Any patient undergoing liver transplant or resection surgery will be asked to participate in the study and assigned to a control or investigational group. Pertinent information will be collected from the medical record including gender, age in years, diagnosis, type of surgery, length of stay, medications used for pain or nausea, and first bowel movement. The subjects will also be asked to keep a journal of their bowel habits, signs and symptoms of gastrointestinal distress/post-operative ileus, use of medications, first bowel movement, satisfaction with bowel management and any additional comments. Aims of the study are to determine the effectiveness of the three arms of this trial for the resolution of POI as noted by first post-operative bowel movement; to determine if there is a difference in the length of stay based on the interventions; and to determine if there is a difference in patient satisfaction based on the intervention.

Interventions

DRUGstool softener

ducosate sodium, Milk of Magnesia, dulcolax

DEVICEArm B: Acupressure bracelet

Bioband

DIETARY_SUPPLEMENTsugar free gum

Orbit

Sponsors

University of Nebraska
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients 19 years or older who speak and read English and have had a liver transplant or liver resection surgery

Exclusion criteria

* Patients less than 19 years of age having liver transplant or liver resection surgery * Non-English speaking * Pregnancy

Design outcomes

Primary

MeasureTime frameDescription
Timing of first post operative bowel movementDays post operativeFirst bowel movement

Secondary

MeasureTime frameDescription
Length of hospital stayTime from admission to discharge post surgeryLength of stay

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026