Normal
Conditions
Keywords
Atopy patch test
Brief summary
Atopy patch test in normal population
Detailed description
The initial diagnostic work up of suspected food allergy includes patient's history, skin prick test (SPT), measurement of food specific immunoglobulin E (IgE) with serological assays, and more recently the atopy patch test. A positive SPT seems to reflect early reactions to food challenges, whereas the atopy patch test has a high diagnostic efficacy for late phase clinical reactions. The purpose of this study was to evaluate atopy patch test reaction in non-atopic population.
Interventions
Atopy patches used with food lyophilized allergen and commercial allergen were placed on back of subjects for 48 hrs then atopy patches were taken off. Subjects should return to evaluate reaction one day later(72 hrs after applying atopy patch test)
Sponsors
Mahidol University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy volunteer * Age 18-40 yrs * Volunteer sign for informed consent
Exclusion criteria
* who have dermographism * who have chronic disease eg.autoimmune disease, immune deficiency, cancer or allergic disease * pregnant women * who have severe eczema * who receive antihistamine, topical steroid and systemic steroid \> 20 mg/day within 7 days prior study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Reaction of atopy patch test | 3 days | To evaluate outcome of atopy patch test reaction in non-atopic subject |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Comparisons atopy patch test reaction between lyophilized allergen and commercial allergen | 3 days | To compare outcome of atopy patch test reaction using lyophilized allergen and commercial allergen |
Countries
Thailand
Outcome results
None listed