Pressure Support During Chest Wall Compression

Increasing Pressure Support During Chest Wall Compression is Useful During Respiratory Therapy?

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01155648

Enrollment

Registered

2010-07-02

Start date

2008-05-31

Completion date

2010-05-31

Last updated

2010-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critical Care, Respiration, Artificial

Keywords

Mechanical ventilation, Chest physiotherapy, Chest wall compression

Brief summary

The purpose of this study is to compare two physiotherapy techniques: chest wall compression versus chest wall compression plus increase of 10 cmH2O in inspiratory pressure.

Detailed description

1. After being placed in the supine position in bed, with head angle elevation at 30°, patients were randomized to:group 1 (G1): chest wall compression for ten minutes in chest or group 2 (G2): chest wall compression plus increase of 10 cmH2O in IP in PSV for ten minutes in chest. 2. Clinical variables and APACHE II were registered. 3. Parameters analyzed at the beginning (1) and at the end (2) of the protocol were: variation of peak pressure (ΔPp=Pp2-Pp1),variation of tidal volume (ΔVT =VT2-VT1), variation of dynamic compliance (ΔCdyn= Cdyn2-Cdyn1). 4. The amount of variation of mucus secretion aspirated (ΔSa= Sa2-Sa1) at the end was also measured

Interventions

DEVICEChest wall compression plus increase of 10 cmH2O in inspiratory pressure during Pressure Support Ventilation for ten minutes in chest.

DEVICEChest wall compression for ten minutes in chest

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients on mechanical ventilation over 48 hours * With ventilatory drive * Hemodynamically stable MAP\> 60 mmHg * With treatment of respiratory therapy

Exclusion criteria

* Contra indication of increased positive inspiratory pressure * Peak pressure in the upper airway \> 40 cmH2O * Osteoporosis diagnosis * Deny to participate in the study

Design outcomes

Primary

Measure	Time frame
Variation of mucus secretion aspirated.	Two years

Secondary

Measure	Time frame	Description
Hemodynamic and pulmonary parameters.	Two years	The hemodynamic and pulmonary parameters were collected: Hart rate (HH), respiratory rate (f), mean arterial pressure (MAP) and peripheral arterial saturation of oxygen (SpO2); peak inspiratory pressure (Ppeak),and Tidal volume (VT) measured in the ventilator, dynamic compliance (Cdyn calculated through the formula VT/ Ppeak - PEEP)

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 30, 2026