Effectiveness of a Ready-to-Use-Food (RUF) Supplement to Prevent Acute Child Malnutrition

Effectiveness and Cost-effectiveness of a Ready-to-Use-Food (RUF) Supplement to Prevent Acute Malnutrition in Children Between 6-36 Months in Urban Chad

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01154595

Acronym

PREAMA

Enrollment

2000

Registered

2010-07-01

Start date

2010-06-30

Completion date

2011-02-28

Last updated

2011-10-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Child, Malnutrition

Keywords

moderate acute malnutrition, prevention, Lipid-based supplement

Brief summary

The overall objective of this project is to assess the effectiveness and cost-effectiveness of RUF (ready-to-Use Food, Plumpy Doz(r)) to prevent moderate acute malnutrition in children aged 6-36 months if embedded in a program of conditional household food assistance.

Interventions

DIETARY_SUPPLEMENTPlumpy Doz(r) - Ready-to-Use Food

47g Plumpy Doz(r) per day per child

BEHAVIORALFood-for-Training

Conditional family food supplementation (sugar, sorghum, beans, iodized salt, vegetable oil) 1800 kcal/person/day in function of attendance and participation in a sensitization program covering various themes on household, water and disease management, hygiene promotion, sanitation and dietary practices for children.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

6 Months to 36 Months

Healthy volunteers

Yes

Inclusion criteria

* WH≥80% of median of NCHS reference without bilateral pitting oedema; * Age ≥ 6 months and ≤36 months; * Member of a household with a dependency ratio \>4; * Not planning to leave the study zone for the coming 5 months;

Exclusion criteria

* Not showing appetite; * Age \< 6 months or age \> 36 months * Weight-for-Height Z-score \<-2 and/or the presence of bilateral pitting oedema in children 6-36 months; * Member of a household with a dependency ration ≤ 4; * Clinical complications * Presence of chronic illness, cardiac disease, congenital abnormalities, cancer; * Being allergic to one of the ingredients of the RUF.

Design outcomes

Primary

Measure	Time frame
Cumulative wasting incidence, hemoglobin concentration	monthly

Secondary

Measure	Time frame
weight gain	monthly
time to become wasted	monthly
default rate	monthly
RUF acceptability	monthly
dietary intake	monthly

Countries

Chad

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 25, 2026