RETRIeVE: ReversE TranscRiptase Inhibitor hiV Practice

Non-nucleoside Reverse Transcriptase Inhibitor Failure in a High HIV Caseload Australian Primary Care Practice

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01154556

Enrollment

2044

Registered

2010-07-01

Start date

2010-06-30

Completion date

2013-02-28

Last updated

2015-09-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV Positive

Keywords

Antiretroviral therapy experienced, failed NNRTI regime

Brief summary

An observational retrospective study of NNRTI experienced patients who have virologically failed. The study aims to assess resistance profiling and subsequent prescription patterns of patients on NNRTIs

Detailed description

This is a cross-sectional study involving retrospective review of HIV-1 positive patient records who began treatment with a non-nucleoside reverse transcriptase inhibitor (NNRTI) and subsequently failed. Patients who have virologically failed previous NNRTI treatment, or have resistance to 1 drug in the NNRTI class are examined further. Such patients will have attended the clinic every 3-6 months for routine medical care. The data source for variables collected is the patient's electronic medical records. This database is located at Holdsworth House Medical Practice (HHMP), Sydney.

Interventions

None listed

Study design

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

1. Documented HIV infection 2. Attended Holdsworth House Medical Practice 1999-2009. 3. Chosen ART regime includes an NNRTI

Exclusion criteria

N/A

Design outcomes

Primary

Measure	Time frame
resistance profiling and subsequent prescription patterns of patients on NNRTIs	1 year

Countries

Australia

Outcome results