Diabetes Mellitus, Type 2
Conditions
Keywords
Insulin resistance, Insulin deficiency, HOMA-IR, Drug naive, Diabetes mellitus, type II
Brief summary
The purpose of this study is investigating the clinical characteristics of newly diagnosed, drug naïve type 2 diabetic patients according to insulin secretion and insulin resistance.
Detailed description
Primary Objective:To investigate whether insulin resistance or insulin deficiency is primary in the pathogenesis of type 2 diabetes mellitus in Korea Secondary Objectives:To investigate proportion of patients with severe insulin deficiency at diagnosis,To investigate proportion of metabolic syndrome in patients with newly diagnosed, drug-naïve type 2 diabetes mellitus,To investigate proportion of obesity in patients with newly diagnosed, drug-naïve type 2 diabetes mellitus
Interventions
OTHERHOMA-IR
Blood sampling for HOMA-IR and HbA1C, fasting glucose, C-peptide, Lipid profile
Sponsors
GlaxoSmithKline
Study design
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Newly diagnosed, drug naïve type 2 DM patients who gave informed consent, Diagnosis of type 2 DM will be made according to ADA guideline 2009
Exclusion criteria
Patients age under 18 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| insulin resistance assessed using HOMA-IR | within 3months after DM diagnosis |
Secondary
| Measure | Time frame |
|---|---|
| proportion of patients with severe insulin deficiency assessed using C-peptide | within 3months after DM diagnosis |
| proportion of metabolic syndrome in patients | within 3months after DM diagnosis |
| proportion of obesity in patients | within 3months after DM diagnosis |
Countries
South Korea
Outcome results
None listed