Emergency Agitation in T&A

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01152476

Enrollment

Registered

2010-06-29

Start date

2010-04-30

Completion date

2010-10-31

Last updated

2011-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

healthy pediatric patients undergoing tonsillectomy and adenoidectomy

Brief summary

Sevoflurane has been used commonly in pediatric anesthesia since 1990. However, it has caused more emergency agitation (EA) that other inhalation agents and the incidence is up to 80%. Therefore, lower minimum alveolar concentration of sevoflurane will reduce the EA when it is used with remifentanil in pediatric general anesthesia.

Interventions

DRUGremifentanil

General anesthesia is maintained witn sevoflurane and remifentanil.

DRUGnormal saline

General anesthesia is maintained with only sevoflurane and with normal saline instead of remifentanil

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

2 Years to 6 Years

Healthy volunteers

Inclusion criteria

* American Society of Anesthesiologist physical status I or II * 2-6 year-old children * patients undergoing tonsillectomy and adenoidectomy

Exclusion criteria

* upper respiratory disease * mental retardation

Design outcomes

Primary

Measure	Time frame	Description
emergency agitation	during 1 hour after recovering of anesthesia	at post-anesthetic care unit

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026