Dyspepsia, Lack of Satiety
Conditions
Keywords
oxytocin, satiety, dyspepsia
Brief summary
The investigators have seen that oxytocin lowers satiety in healthy subjects. Patients with dyspepsia suffers from decreased accommodation and increased satiety postprandially. The investigators now want to examine whether oxytocin may diminish symptoms in these patients.
Detailed description
Patients will come twice for a slow satiety drinking test. Once they will get saline infusion and once oxytocin 40 mU/min. At the same time they register satiety on a VAS scale.
Interventions
DRUGoxytocin
40mU/min as infusion of oxytocin
Sponsors
Skane University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Dyspepsia
Exclusion criteria
* Age \> 65 years * Cardiac disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Satiety | 2 h | The investigator want to examine whether oxytocin leads to lower satiety scores after intake of the same volume of nutrient |
Other
| Measure | Time frame | Description |
|---|---|---|
| To see if oxytocin lowers satiety | 2h | To perform a drinking satiety test twice. Once with oxytocin and once with saline. Then examine whether oxytocin decreases satiety compared to saline |
Countries
Sweden
Outcome results
None listed