Morbid Obesity
Conditions
Brief summary
The majority of data documenting the outcomes for the adjustable gastric band (LAGB) originate from non-publicly funded surgical centres. The investigators aim to investigate the clinical outcomes of LAGB from a publicly funded Canadian obesity management program. This program recognized obesity as a chronic disease, providing extensive pre-operative multidisciplinary assessment and long term patient follow-up. Patients are selected for surgical management carefully by a multidisciplinary team and the LAGB is presented as one option to surgical management. Further, the investigators will investigate the operational impacts, including direct and indirect costs related the LAGB, to determine long term impacts on publicly funded hospitals within Canada.
Interventions
None listed
Sponsors
Alberta Health services
University of Alberta
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All patients seen within the Weight Wise program and selected for surgical management, who have undergone LAGB will be included in this analysis.
Exclusion criteria
* Patients who have undergone selection for surgery outside this process, or who have had surgery elsewhere.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mean Percentage Total Body Weight Loss | baseline to 1 year, baseline to 2 years, baseline to 3 years | the percent total body weight loss between Baseline and 1 year the percent total body weight loss between Baseline and 2 years the percent total body weight loss between Baseline and 3 years |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| % of Excess Body Weight Loss | baseline to 1 year, baseline to 2 years, baseline to 3 years | the percent of excess body weight loss between Baseline and 1 year the percent of excess body weight loss between Baseline and 2 years the percent of excess body weight loss between Baseline and 3 years |
Countries
Canada
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| LAGB Patients in Weight Wise Program All patients seen within the Weight Wise program and selected for surgical management, who have undergone LAGB will be included in this analysis. | 178 |
| Total | 178 |
Baseline characteristics
| Characteristic | LAGB Patients in Weight Wise Program |
|---|---|
| Age, Continuous | 42.8 years STANDARD_DEVIATION 10.4 |
| initial BMI | 44.2 kg/m^2 STANDARD_DEVIATION 7 |
| Sex: Female, Male Female | 153 Participants |
| Sex: Female, Male Male | 25 Participants |
Adverse events
| Event type | EG000 affected / at risk |
|---|---|
| deaths Total, all-cause mortality | — / — |
| other Total, other adverse events | 50 / 178 |
| serious Total, serious adverse events | 0 / 178 |
Outcome results
Primary
Mean Percentage Total Body Weight Loss
the percent total body weight loss between Baseline and 1 year the percent total body weight loss between Baseline and 2 years the percent total body weight loss between Baseline and 3 years
Time frame: baseline to 1 year, baseline to 2 years, baseline to 3 years
Population: Three patients' weight data were not included in the weight loss analysis owing to early removal of band (n = 1) and complication or pregnancy affecting weight (n = 2) before 1-year follow-up. 79 patients reached 2 year follow up time point and 38 patients reached 3 year follow up time point.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| LAGB Patients in Weight Wise Program | Mean Percentage Total Body Weight Loss | Baseline to 1 year | 15.8 % of total body weight loss | Standard Deviation 7.6 |
| LAGB Patients in Weight Wise Program | Mean Percentage Total Body Weight Loss | Baseline to 2 years | 20.7 % of total body weight loss | Standard Deviation 11 |
| LAGB Patients in Weight Wise Program | Mean Percentage Total Body Weight Loss | Baseline to 3 years | 20.3 % of total body weight loss | Standard Deviation 10 |
Secondary
% of Excess Body Weight Loss
the percent of excess body weight loss between Baseline and 1 year the percent of excess body weight loss between Baseline and 2 years the percent of excess body weight loss between Baseline and 3 years
Time frame: baseline to 1 year, baseline to 2 years, baseline to 3 years
Population: 3 not included the same reason as above.
| Arm | Measure | Group | Value (MEAN) | Dispersion |
|---|---|---|---|---|
| LAGB Patients in Weight Wise Program | % of Excess Body Weight Loss | Baseline to 1 year | 34.1 % of excessive weight loss | Standard Deviation 16 |
| LAGB Patients in Weight Wise Program | % of Excess Body Weight Loss | Baseline to 2 years | 44 % of excessive weight loss | Standard Deviation 23 |
| LAGB Patients in Weight Wise Program | % of Excess Body Weight Loss | Baseline to 3 years | 43.4 % of excessive weight loss | Standard Deviation 21 |