Effects of Chloral Hydrate on Induction, Maintenance, and Recovery From Sevoflurane Anesthesia in Day-case Pediatric Surgery

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01149226

Enrollment

100

Registered

2010-06-28

Start date

2010-05-31

Completion date

2010-12-31

Last updated

2011-06-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric

Keywords

pediatric patients, ASA physical status I or II, aged between 1-5 yrs

Brief summary

Effects of Choral Hydrate on Induction, Maintenance, and Recovery from Sevoflurane Anesthesia in Day-case Pediatric Surgery

Interventions

DRUGchloral hydrate

30 min before the induction of anesthesia, chloral hydrate (40 mg/kg) or placebo was administered to the children orally.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

ALL

Age

1 Years to 5 Years

Healthy volunteers

Inclusion criteria

1. ASA I or II 2. 1-5 years children 3. elective day-case orchiopexy

Exclusion criteria

1. congenital hear disease 2. renal disease 3. liver disease 4. growth retardation 5. coagulopathy

Design outcomes

Primary

Measure	Time frame	Description
Preoperative Anxiety	—	Preoperative Anxiety Score Modified Yale Preoperative Anxiety Scale (YPAS, 0-100) was assessed by observer Anesth Analg 1997;85:783-8
Induction Compliance	—	Induction Compliance Checklist Induction Compliance Checklists (ICC, 0-10) was assessed by anesthetist Anesthesiology 1998;89:1147-56
Postoperative Pain	—	-Postoperative Pain Score Face, Legs, Activity, Cry, Consolability (FLACC) Behavioral Scale (0-10) was assessed by observer Am J Crit Care. 2010 Jan;19(1):55-61
Posthospitalization Behavior	—	Posthospitalization Behavior Questionnaire Posthospitalization Behavioural Questionnaire (27-135)was sent to all parents of children Paediatr Anaesth. 2001 Nov;11(6):719-23.

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026